Title:
ULTRARAPID ACTING INSULIN FORMULATION
Document Type and Number:
Japanese Patent JP2017226689
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide an ultrarapid acting insulin preparation to be administered to a patient in need of treatment with an ultrarapid acting insulin preparation in beginning a daily meal.SOLUTION: An ultrarapid acting insulin preparation comprises a fumaryl diketopiperazine associated with insulin, and provides the rise in the blood insulin concentration which peaks within 20-30 minutes after the administration. The initial dose expressed in subcutaneous equivalent units is 1-5 subcutaneous equivalent units, preferably 1-4 subcutaneous equivalent units, further preferably 1-2 subcutaneous equivalent units. The administering step does not comprise an injection, and the preparation is administered to a patient by inhalation.SELECTED DRAWING: Figure 6
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Inventors:
PETER RICHARDSON
ROBERT A BAUGHMAN
ELIZABETH POTOCKA
ANDERS HASAGER BOSS
RICHARD PETRUCCI
CAMPBELL HOWARD
ALFRED MANN
ROBERT A BAUGHMAN
ELIZABETH POTOCKA
ANDERS HASAGER BOSS
RICHARD PETRUCCI
CAMPBELL HOWARD
ALFRED MANN
Application Number:
JP2017152242A
Publication Date:
December 28, 2017
Filing Date:
August 07, 2017
Export Citation:
Assignee:
MANNKIND CORP
International Classes:
A61K38/28; A61K9/72; A61K47/54; A61P3/10
Domestic Patent References:
| JP2008526893A | 2008-07-24 |
Foreign References:
| WO2007016600A2 | 2007-02-08 | |||
| WO2006105501A2 | 2006-10-05 |
Other References:
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ＤＩＡＢＥＴＥＳ ＣＡＲＥ, vol. 30, no. 9, JPN6016003824, 2007, pages 2307 - 2308, ISSN: 0003783577
ＪＯＵＲＮＡＬ ＯＦ ＤＩＡＢＥＴＥＳ ＳＣＩＥＮＣＥ ＡＮＤ ＴＥＣＨＮＯＬＯＧＹ, vol. 2, no. 1, JPN6016003827, January 2008 (2008-01-01), pages 47 - 57, ISSN: 0003783578
ＥＸＰＥＲＩＭＥＮＴＡＬ ＡＮＤ ＣＬＩＮＩＣＡＬ ＥＮＤＯＣＲＩＮＯＬＯＧＹ ＡＮＤ ＤＩＡＢＥＴ, vol. 110, no. 1, JPN6014002959, 2002, pages 17 - 21, ISSN: 0003783579
ＪＯＵＲＮＡＬ ＯＦ ＤＩＡＢＥＴＥＳ ＳＣＩＥＮＣＥ ＡＮＤ ＴＥＣＨＮＯＬＯＧＹ, vol. 2, no. 2, JPN6016003830, May 2008 (2008-05-01), pages 205 - 212, ISSN: 0003783580
ＤＩＡＢＥＴＥＳ ＣＡＲＥ, vol. 30, no. 9, JPN6016003824, 2007, pages 2307 - 2308, ISSN: 0003783577
ＪＯＵＲＮＡＬ ＯＦ ＤＩＡＢＥＴＥＳ ＳＣＩＥＮＣＥ ＡＮＤ ＴＥＣＨＮＯＬＯＧＹ, vol. 2, no. 1, JPN6016003827, January 2008 (2008-01-01), pages 47 - 57, ISSN: 0003783578
ＥＸＰＥＲＩＭＥＮＴＡＬ ＡＮＤ ＣＬＩＮＩＣＡＬ ＥＮＤＯＣＲＩＮＯＬＯＧＹ ＡＮＤ ＤＩＡＢＥＴ, vol. 110, no. 1, JPN6014002959, 2002, pages 17 - 21, ISSN: 0003783579
ＪＯＵＲＮＡＬ ＯＦ ＤＩＡＢＥＴＥＳ ＳＣＩＥＮＣＥ ＡＮＤ ＴＥＣＨＮＯＬＯＧＹ, vol. 2, no. 2, JPN6016003830, May 2008 (2008-05-01), pages 205 - 212, ISSN: 0003783580
Attorney, Agent or Firm:
Kimura Mitsuru
Takanori Mamoru
Taiji Morikawa
Kei Sakurada
Mie Hideki
Takanori Mamoru
Taiji Morikawa
Kei Sakurada
Mie Hideki