To provide a new support for effectively proliferating immature blood cells (hereinafter referred to as HSC) including hematopoietic stem cell existing in trace amount and to provide a method for effectively proliferating and producing HSC by using the support.
The support for promoting proliferation of HSC is composed of a partially decomposed polymerizable extracellular matrix (ECM) protein in which polymerization ability is retained and cellular adhesiveness is lowered. The method for producing HSC comprises partially decomposing a polymerizable ECM protein to provide a partially decomposed polymerizable ECM protein in which polymerization ability of a protein is retained and cellular adhesiveness is lowered, adding the ECM protein to clot (a material obtained by coagulating plasma obtained by excluding a hemocyte ingredient in blood), using the resultant material as a support for promoting proliferation of HSC, culturing a blood cell containing the HSC and proliferating and producing the HSC.
CHO GAKUGUN
Yoshiko Akiyama
Yoshiro Kurauchi
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