Title:
SYK INHIBITORS
Document Type and Number:
Japanese Patent JP2018083837
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide Syk inhibitors for treatment of disease states such as cancer and inflammatory conditions.SOLUTION: The invention provides compounds represented by formula I. [Ris 1-N-(2-oxethyl)-4-piperazyl, 1-N-(2-dimethylol) or S or E3-thylol-1,N morphonyl; Ris H or 2-hydroxyethoxyl; and Rand Rare each independently H or methyl.]SELECTED DRAWING: None
Inventors:
PETER A BLOMGREN
ASTRID CLARKE
KEVIN S CURRIE
JULIE DI PAOLO
JEFFREY E KROPF
LEE SEUNG H
JENNIFER R LO
SCOTT A MITCHELL
AARON C SCHMITT
SUNDARAMOORTHI SWAMINATHAN
XIONG JIN-MING
XU JIANJUN
ZHAO ZHONGDONG
ASTRID CLARKE
KEVIN S CURRIE
JULIE DI PAOLO
JEFFREY E KROPF
LEE SEUNG H
JENNIFER R LO
SCOTT A MITCHELL
AARON C SCHMITT
SUNDARAMOORTHI SWAMINATHAN
XIONG JIN-MING
XU JIANJUN
ZHAO ZHONGDONG
Application Number:
JP2018009516A
Publication Date:
May 31, 2018
Filing Date:
January 24, 2018
Export Citation:
Assignee:
GILEAD SCIENCES INC
International Classes:
C07D487/04; A61K31/475; A61K31/4985; A61K45/00; A61P1/04; A61P3/10; A61P5/14; A61P7/04; A61P7/06; A61P9/00; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P11/08; A61P13/12; A61P17/00; A61P17/16; A61P19/02; A61P19/06; A61P19/08; A61P21/00; A61P21/04; A61P25/00; A61P25/16; A61P25/28; A61P29/00; A61P31/04; A61P35/00; A61P35/02; A61P37/06; A61P37/08
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita
Previous Patent: 被覆電線、端子付き電線、銅合金線、及び銅合金撚線
Next Patent: Those use as 6- (5-hydroxy 1H- Pyrazole - 1- Il ) nicotinamide derivative and PHD inhibitor
Next Patent: Those use as 6- (5-hydroxy 1H- Pyrazole - 1- Il ) nicotinamide derivative and PHD inhibitor