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Title:
癌を治療するための生体影響性化合物の標的送達
Document Type and Number:
Japanese Patent JP2004532245
Kind Code:
A
Abstract:
A homogeneous conjugate for targeting and treating diseased cells wherein the conjugate comprises an anti-cancer drug and a targeting protein, wherein said anti-cancer drug is selected from the group consisting of heat sensitizers, photosensitizers and apoptosis inducing compounds, a method for making such a conjugate, and methods for using the conjugate. The targeting protein is preferably transferrin.

Inventors:
Fork page double
Application Number:
JP2002590988A
Publication Date:
October 21, 2004
Filing Date:
May 15, 2002
Export Citation:
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Assignee:
Fork page double
International Classes:
A61K31/16; A61K31/195; A61K31/277; A61K31/282; A61K31/409; A61K31/495; A61K31/7028; A61K31/704; A61K31/714; A61K33/24; A61K33/26; A61K38/18; A61K38/31; A61K38/40; A61K41/00; A61K45/00; A61K47/48; A61P35/00; (IPC1-7): A61K47/48; A61K31/16; A61K31/195; A61K31/277; A61K31/282; A61K31/409; A61K31/704; A61K33/24; A61K33/26; A61K41/00; A61K45/00; A61P35/00
Domestic Patent References:
JPS60501951A1985-11-14
JPS63502747A1988-10-13
JPH07505661A1995-06-22
JPH06502177A1994-03-10
JP2002095476A2002-04-02
JP2004528309A2004-09-16
Other References:
JPN6008038998, Anticancer Research, 1994, Vol.14,No.2A, p397−403
JPN5003018360, WANG, F., ANTICANCER RESEARCH, 2000, V20N2A, P799−808
JPN5003018361, FAULK, W.P., MOLECULAR BIOTHERAPY, 1990, V2, P57−60
JPN6008039000, Journal of Pharmaceutical Sciences, 1998, Vol.87,No.3, p338−346
JPN6008039014, Biochemical Pharmacology, 1996, Vol.51,No.4, p489−493
Attorney, Agent or Firm:
Daisuke Tanaka