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Title:
化合物およびPDE4活性剤としてのそれらの使用
Document Type and Number:
Japanese Patent JP7062643
Kind Code:
B2
Abstract:
Compounds of Formula I, which are activators of long form cyclic nucleotide phosphodiesterase-4 (PDE4) enzymes (isoforms) are provided. Methods and uses of these compounds for the treatment or prevention of disorders requiring a reduction of second messenger responses mediated by cyclic 3′,5′-adenosine monophosphate (cAMP) are also described.

Inventors:
Adam Julia Marie
Adams David Roger
Application Number:
JP2019515286A
Publication Date:
May 06, 2022
Filing Date:
September 28, 2017
Export Citation:
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Assignee:
Milonid Limited
International Classes:
C07D231/12; A61K31/415; A61K31/4196; A61K31/4439; A61P1/16; A61P3/10; A61P5/16; A61P5/20; A61P5/28; A61P5/38; A61P9/00; A61P13/08; A61P13/12; A61P19/08; A61P31/04; A61P31/06; A61P31/18; A61P35/00; A61P35/02; A61P37/04; A61P43/00; C07D231/14; C07D233/64; C07D249/10; C07D401/04; C07D403/12
Domestic Patent References:
JP51082269A
JP2006523719A
JP2006518738A
JP2007514676A
JP2018515594A
JP2012520834A
Foreign References:
US20090186900
Other References:
STN International,CAS Registry No. 1390593-23-3、1389982-71-1, 1389956-05-1, 1387237-35-5, 1387237-06-0, 1386599-13-8, 1386223-24-0, 1385933-63-0, 1355855-72-9, 1333866-08-2, 1333722-54-5, 1290014-46-8, 1279953-11-5,File REGISTRY (online),Entered STN,2012年08月12日
Attorney, Agent or Firm:
Kazunori Tsujinaga