Title:
Those use as an N-prop 2-in dolphin Ruboxamide derivative and TRPA1 antagonist
Document Type and Number:
Japanese Patent JP6226991
Kind Code:
B2
Abstract:
Compounds of formula I, wherein A, B, X, Z and R1-R6, are as defined in the claims, exhibit TRPA 1 activity and are thus useful as TRPA1 modulators.
Inventors:
Arbella, Lina
Heikkinen, Telhi
Holm, Patrick
Pulcis, Peteris
Los Lund, Match Ass
Salo, Harri
Heikkinen, Telhi
Holm, Patrick
Pulcis, Peteris
Los Lund, Match Ass
Salo, Harri
Application Number:
JP2015533645A
Publication Date:
November 08, 2017
Filing Date:
September 30, 2013
Export Citation:
Assignee:
Orion Corporation
International Classes:
C07C237/30; A61K31/166; A61K31/277; A61K31/357; A61K31/36; A61K31/381; A61K31/404; A61K31/44; A61K31/444; A61K31/47; A61K31/505; A61K31/5355; A61K45/00; A61P1/00; A61P3/10; A61P11/00; A61P11/06; A61P19/02; A61P25/00; A61P25/04; A61P25/06; A61P29/00; A61P43/00; C07D209/08; C07D213/81; C07D213/82; C07D215/48; C07D239/42; C07D317/62; C07D319/18; C07D321/10; C07D333/38; C07D407/12; C07D417/12
Domestic Patent References:
| JP50082075A |
Other References:
Bioorganic & Medicinal Chemistry Letters,2012年,Vol. 22,5485-5492
Pharmazie,1992年,Vol. 47,18-20
Pharmazie,1992年,Vol. 47,18-20
Attorney, Agent or Firm:
Asahina Patent Office
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