Title:
【発明の名称】クラミジア感染の処置および診断のための化合物および方法
Document Type and Number:
Japanese Patent JP2002531129
Kind Code:
A
Abstract:
Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
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Inventors:
Probst, Peter
Berthier, Ajay
Ski Key, Yasar A. W.
Flynn, Stephen Pee
Jen, Cheyenne
Stromberg, Erica Jean
Berthier, Ajay
Ski Key, Yasar A. W.
Flynn, Stephen Pee
Jen, Cheyenne
Stromberg, Erica Jean
Application Number:
JP2000586916A
Publication Date:
September 24, 2002
Filing Date:
December 08, 1999
Export Citation:
Assignee:
Corixa Corporation
International Classes:
G01N33/53; A61K35/12; A61K38/00; A61K39/118; A61K39/395; A61K45/00; A61K48/00; A61P33/00; C07K14/295; C07K16/12; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/31; C12P21/08; C12Q1/68; G01N33/532; G01N33/569; A61K39/00; C12R1/01; (IPC1-7): C12N15/09; A61K35/12; A61K38/00; A61K39/118; A61K39/395; A61K45/00; A61K48/00; A61P33/00; C07K14/295; C07K16/12; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/08; C12Q1/68; G01N33/53; G01N33/532; G01N33/569
Domestic Patent References:
| JPH10509325A | 1998-09-14 |
Foreign References:
| WO1999028475A2 | 1999-06-10 |
Other References:
JPN6009068253, ＳＴＥＰＨＥＮＳ，Ｒ．Ｓ． ｅｔ ａｌ, "Ｇｅｎｏｍｅ ｓｅｑｕｅｎｃｅ ｏｆ ａｎ ｏｂｌｉｇａｔｅ ｉｎｔｒａｃｅｌｌｕｌａｒ ｐａｔｈｏｇｅｎ ｏｆ ｈｕｍａｎｓ： Ｃｈｌａｍｙｄｉａ ｔｒａｃｈｏｍａｔｉｓ", Ｓｃｉｅｎｃｅ, 1998, Ｖｏｌ．２８２， Ｎｏ．５３８９, ｐ．７５４−９
JPN6009068255, ＫＡＵＬ，Ｒ． ｅｔ ａｌ, "Ｃｌｏｎｉｎｇ， ｅｘｐｒｅｓｓｉｏｎ， ａｎｄ ｐｒｉｍａｒｙ ｓｔｒｕｃｔｕｒｅ ｏｆ ａ Ｃｈｌａｍｙｄｉａ ｔｒａｃｈｏｍａｔｉｓ ｂｉｎｄｉｎｇ ｐｒｏｔｅｉｎ", Ｊ Ｂａｃｔｅｒｉｏｌ, 1987, Ｖｏｌ．１６９， Ｎｏ．１１, ｐ．５１５２−６
JPN6009068257, ＫＡＬＭＡＮ，Ｓ． ｅｔ ａｌ, "Ｃｏｍｐａｒａｔｉｖｅ ｇｅｎｏｍｅｓ ｏｆ Ｃｈｌａｍｙｄｉａ ｐｎｅｕｍｏｎｉａｅ ａｎｄ Ｃ． ｔｒａｃｈｏｍａｔｉｓ", Ｎａｔ Ｇｅｎｅｔ, 19990401, Ｖｏｌ．２１， Ｎｏ．４, ｐ．３８５−９
JPN6009068259, ＫＯＲＮＡＫ，Ｊ．Ｍ． ｅｔ ａｌ, "Ｓｅｑｕｅｎｃｅ ａｎａｌｙｓｉｓ ｏｆ ｔｈｅ ｇｅｎｅ ｅｎｃｏｄｉｎｇ ｔｈｅ Ｃｈｌａｍｙｄｉａ ｐｎｅｕｍｏｎｉａｅ ＤｎａＫ ｐｒｏｔｅｉｎ ｈｏｍｏｌｏｇ", Ｉｎｆｅｃｔ Ｉｍｍｕｎ, 1991, Ｖｏｌ．５９， Ｎｏ．２, ｐ．７２１−５
JPN6009068255, ＫＡＵＬ，Ｒ． ｅｔ ａｌ, "Ｃｌｏｎｉｎｇ， ｅｘｐｒｅｓｓｉｏｎ， ａｎｄ ｐｒｉｍａｒｙ ｓｔｒｕｃｔｕｒｅ ｏｆ ａ Ｃｈｌａｍｙｄｉａ ｔｒａｃｈｏｍａｔｉｓ ｂｉｎｄｉｎｇ ｐｒｏｔｅｉｎ", Ｊ Ｂａｃｔｅｒｉｏｌ, 1987, Ｖｏｌ．１６９， Ｎｏ．１１, ｐ．５１５２−６
JPN6009068257, ＫＡＬＭＡＮ，Ｓ． ｅｔ ａｌ, "Ｃｏｍｐａｒａｔｉｖｅ ｇｅｎｏｍｅｓ ｏｆ Ｃｈｌａｍｙｄｉａ ｐｎｅｕｍｏｎｉａｅ ａｎｄ Ｃ． ｔｒａｃｈｏｍａｔｉｓ", Ｎａｔ Ｇｅｎｅｔ, 19990401, Ｖｏｌ．２１， Ｎｏ．４, ｐ．３８５−９
JPN6009068259, ＫＯＲＮＡＫ，Ｊ．Ｍ． ｅｔ ａｌ, "Ｓｅｑｕｅｎｃｅ ａｎａｌｙｓｉｓ ｏｆ ｔｈｅ ｇｅｎｅ ｅｎｃｏｄｉｎｇ ｔｈｅ Ｃｈｌａｍｙｄｉａ ｐｎｅｕｍｏｎｉａｅ ＤｎａＫ ｐｒｏｔｅｉｎ ｈｏｍｏｌｏｇ", Ｉｎｆｅｃｔ Ｉｍｍｕｎ, 1991, Ｖｏｌ．５９， Ｎｏ．２, ｐ．７２１−５
Attorney, Agent or Firm:
Shusaku Yamamoto