Title:
【発明の名称】Gタンパク質レセプターHTNAD29
Document Type and Number:
Japanese Patent JPH11506341
Kind Code:
A
Abstract:
Human G-protein PAF receptor polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptides for identifying antagonists and agonists to such polypeptides and methods of using the agonists and antagonists therapeutically to treat conditions related to the underexpression and overexpression of the PAF receptor polypeptides. Also disclosed are diagnostic methods for detecting a mutation in the PAF receptor nucleic acid sequences and detecting a level of the soluble form of the receptors in a sample derived from a host.
Inventors:
Lee
Full donor, Rebecca A.
Full donor, Rebecca A.
Application Number:
JP50037996A
Publication Date:
June 08, 1999
Filing Date:
June 06, 1995
Export Citation:
Assignee:
Human Genome Sciences, Inc.
International Classes:
G01N33/50; A61K38/00; A61K39/395; A61K45/00; A61K48/00; A61P7/02; A61P9/08; A61P9/10; A61P29/00; A61P37/08; A61P43/00; C07K14/705; C07K14/72; C07K16/28; C12N5/10; C12N15/09; C12N15/12; C12P21/02; C12P21/08; C12Q1/68; G01N33/15; G01N33/53; C12R1/91; (IPC1-7): C12N15/09; A61K38/00; A61K45/00; A61K48/00; C07K14/705; C07K16/28; C12N5/10; C12P21/02; C12Q1/68; G01N33/15; G01N33/50; G01N33/53
Attorney, Agent or Firm:
Shusaku Yamamoto