Title:
【発明の名称】新規二環式芳香族誘導体、それらの製造法及びそれらの医薬、獣医薬及び化粧料としての使用
Document Type and Number:
Japanese Patent JP2731148
Kind Code:
B2
Abstract:
Bicyclic aromatic compounds, having the following formula: in which: n=0 or 1; R' represents H, OH, C1-C4 alkoxy or C1-C4 acyloxy; R'' represents H or C1-C4 alkoxy; or R' and R'' taken together form an oxo (=O), methano (=CH2) or hydroximino (=N-OH) radical; R represents -CH2OH or -COR7; R7 represents H, OR8, or R8 represents H, C1-C4 alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl or aralkyl, optionally substituted, a sugar residue or where p is 1, 2 or 3 and r' and r'' represent H, lower alkyl, monohydroxyalkyl, optionally interrupted by a heteroatom, polyhydroxyalkyl, optionally substituted aryl or benzyl, an amino acid residue or an aminated sugar residue or taken together with the nitrogen atom to which they are attached form a heterocycle; A represents methylene or dimethylene, substituted or not with lower alkyl, R1, R2, R3 and R4 represent H or lower alkyl, R1 and R3 taken together are capable of forming a methylene or dimethylene radical, when A represents dimethylene; R5 and R6 represent H or methyl, and the salts of said compounds, as well as their optical and geometric isomers. This active compound is employed in pharmaceutical or cosmetic preparations.
Inventors:
JAN MAINAN
JERARU RAN
JERARU MARU
SERUJU RESUTORU
BURAAMU SHUROO
JERARU RAN
JERARU MARU
SERUJU RESUTORU
BURAAMU SHUROO
Application Number:
JP17735087A
Publication Date:
March 25, 1998
Filing Date:
July 17, 1987
Export Citation:
Assignee:
SANTORU INTERN DO RUSHERUSHU DERUMATOROJIKU CIRD
International Classes:
A61K8/42; A61K8/44; A61K8/49; A61K8/60; A61K8/00; A61K31/045; A61K31/11; A61K31/12; A61K31/135; A61K31/15; A61K31/165; A61K31/19; A61K31/215; A61K31/495; A61P11/00; A61P17/00; A61P27/02; A61P35/00; A61Q19/00; C07C27/00; C07C29/143; C07C29/147; C07C33/24; C07C33/34; C07C33/36; C07C33/38; C07C41/00; C07C43/178; C07C45/00; C07C45/30; C07C45/46; C07C47/238; C07C49/76; C07C49/796; C07C49/86; C07C51/00; C07C57/50; C07C59/42; C07C59/54; C07C59/86; C07C63/331; C07C65/17; C07C65/36; C07C67/00; C07C69/616; C07C69/76; C07C213/00; C07C235/32; C07C235/84; C07D295/10; C07C; (IPC1-7): C07C33/34; C07C235/84; C07C235/78; C07C235/34
Other References:
CHEMICAL ABSTRACTS=1979
Attorney, Agent or Firm:
Shigeru Yagita (2 outside)