Title:
【発明の名称】赤血球代用物質
Document Type and Number:
Japanese Patent JP2875629
Kind Code:
B2
Abstract:
A red blood cell surrogate which is composed of a nanocrystalline core particle to which an oxygen carrier such as hemoglobin is bound. An oxygen carrier anchor coating is provided between the nanocrystalline core particle and the oxygen carrier in order to provide binding of the oxygen carrier to the nanocrystalline core particle without denaturing the oxygen carrier or otherwise destroying its oxygen carrying capacity. The nanocrystalline core particle with the oxygen carrier bound thereto is coated with an exterior layer of lipid.
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Inventors:
KOSOFUSUKII NIIRU
GERUMAN ANDORYUU II
SUHONSURAA EDOWAADO II
GERUMAN ANDORYUU II
SUHONSURAA EDOWAADO II
Application Number:
JP51597294A
Publication Date:
March 31, 1999
Filing Date:
November 12, 1993
Export Citation:
Assignee:
YUNIBAASHITEI OBU KARIFUORUNIA
International Classes:
A61K9/50; A61K9/00; A61K9/127; A61K9/16; A61K9/51; A61K31/00; A61K31/70; A61K31/74; A61K31/785; A61K33/44; A61K38/16; A61K38/28; A61K38/40; A61K38/42; A61K38/48; A61K39/12; A61K39/21; A61K47/26; A61K47/48; A61K48/00; A61L31/10; A61P7/08; C07K14/05; C07K14/16; C12N11/14; C12N15/87; A61K38/00; (IPC1-7): A61K9/16; A61K9/50; A61K31/70
Domestic Patent References:
| JP5255111A | ||||
| JP9507680A | ||||
| JP8505788A | ||||
| JP9504790A |
Attorney, Agent or Firm:
Shoichi Hase (2 outside)