Title:
【発明の名称】イリジウム―光学活性ホスフィン錯体及びこれを用いた光学活性アルコールの製造方法
Document Type and Number:
Japanese Patent JP2739254
Kind Code:
B2
Abstract:
An iridium-optically active phosphine complex is represented by the formula: [H2Ir(L<1>)(L<2>)]Y wherein L<1> is an optically active phosphine compound (II) or (III): wherein Ar is a phenyl group or a p- and/or m-lower (C1-4) alkyl-substituted phenyl group: e.g. BINAP, L<2> is a tertiary phosphino compound of formula (IV): wherein Z is a lower (C1-4) alkoxy group or a di-lower alkylamino group and A 1, 2 or 3; Y is BF4, PF6, ClO4 or BPh4, wherein Ph is phenyl. The complex can be synthesised from an optically active phosphine compound L<1> by reaction with [Ir(COD)(CH3CN)2]Y and then with L<2> and hydrogen. The complex is used as catalyst in enantioselective hydrogenations, e.g. of 3-oxotetrahydrothiophene or of an unsaturated ketone, to give optically active products in high yields and in high purity.
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Inventors:
Taketomi Takanao
Susumu Akutagawa
Yukinori Hidenori
Takamasa Hidemasa
Kashima Mashima
Susumu Akutagawa
Yukinori Hidenori
Takamasa Hidemasa
Kashima Mashima
Application Number:
JP26343990A
Publication Date:
April 15, 1998
Filing Date:
October 01, 1990
Export Citation:
Assignee:
Takasago International Corporation
International Classes:
B01J31/24; C07B53/00; C07B61/00; C07C29/145; C07C33/03; C07F9/50; C07F15/00; (IPC1-7): C07F15/00; B01J31/24; C07C29/145; C07C33/03; C07F9/50
Attorney, Agent or Firm:
Miyuki Ariga (2 outside)