Title:
【発明の名称】修飾タンパク質およびそれを用いたウイルス感染症を制御するための医薬製剤
Document Type and Number:
Japanese Patent JP2690813
Kind Code:
B2
Abstract:
The invention relates to pharmaceutical preparations which are suitable for treating or curing viral infections, including influenza and immunodeficiency diseases such as retrovirus infections, including AIDS and AIDS-related diseases, and which can also be used to inhibit fusion of virus-infected cells with non-infected cells, which preparations contain modified proteins or polypeptides as active substance or substance contributing to the action or as carrier for other substances, which are also active, which modified proteins or polypeptides have acquired an additional net negative charge by derivatisation of their amino groups and/or other basic functional groups with a reagent which prevents protonation of basic amino acids and/or other basic functional groups or replaces said basic amino acids and/or other basic functional groups by one or more functional groups having a negative charge, and to modified proteins and polypeptides themselves and the preparation and use thereof.
Inventors:
Janssen Robert Walter
Meyer Dirk Krass Focke
Morema Fleche
Declerk Erik Desiree Alice
Powells Rudy Villefleet Yang
Schols dominic
Meyer Dirk Krass Focke
Morema Fleche
Declerk Erik Desiree Alice
Powells Rudy Villefleet Yang
Schols dominic
Application Number:
JP50642192A
Publication Date:
December 17, 1997
Filing Date:
February 24, 1992
Export Citation:
Assignee:
Lakes Uniferge Tate Te Groningen
International Classes:
A61K38/38; A61P31/12; A61P31/16; A61K38/00; A61P31/18; C07K1/107; C07K1/113; C07K14/00; C07K14/76; (IPC1-7): C07K14/00; A61K38/00; C07K1/113
Domestic Patent References:
| JPH02275824A | 1990-11-09 |
Attorney, Agent or Firm:
Bunji Kamata (2 outside)