Title:
【発明の名称】新規な芳香族ナフチル化合物、その製造法及びそれを含む製薬又は化粧料組成物
Document Type and Number:
Japanese Patent JP2760985
Kind Code:
B2
Abstract:
An aromatic naphthyl compound of the formula (I) wherein n is 0 or 1, R' is hydrogen, OH, acyloxy, alkoxy or NH2, R'' is hydrogen or lower alkoxy, or R' and R'' taken together form an oxo, methano or hydroxy-imino radical, R is -CH2OH or -COR8, R8 is hydrogen, -OR9 or R9 is hydrogen, alkyl having 1-20 carbon atoms, mono or polyhydroxyalkyl, aryl, aralkyl, the residue of a sugar or is 1, 2 or 3, r' and r'' each independently represent hydrogen, alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl, benzyl, the residue of amino acid or the residue of aminated sugar, or r' and r'' together form a heterocycle, R1, R2, R3 and R4 represent hydrogen, lower alkyl, alkoxy having 1-4 carbon atoms, fluoroalkoxy, CF3, cycloalkyl, lower acyl, halogen, OH, amino, acylamino or alkoxy carbonyl, R5, R6 and R7 represent hydrogen or methyl or when n=1, R5 and R7 taken together can form with the benzene ring a naphthalene ring, and the salts of the compound of formula I or their geometric or optical isomers. These compounds are useful in human and veterinary medicine and in cosmetic compositions.
Inventors:
JAN MAINAN
JERARU RAN
JERARU MARU
SERUJU RESUTORU
BURAAMU SHUROO
JERARU RAN
JERARU MARU
SERUJU RESUTORU
BURAAMU SHUROO
Application Number:
JP12504387A
Publication Date:
June 04, 1998
Filing Date:
May 23, 1987
Export Citation:
Assignee:
ROREARU
International Classes:
A61K8/00; A61K8/30; A61K8/34; A61K8/35; A61K8/36; A61K8/368; A61K8/37; A61K8/41; A61K8/42; A61K8/49; A61K31/045; A61K31/085; A61K31/12; A61K31/16; A61K31/165; A61K31/19; A61K31/215; A61P17/00; A61P29/00; A61P37/08; C07C29/143; C07C33/18; C07C33/26; C07C33/28; C07C33/32; C07C33/46; C07C41/18; C07C43/14; C07C41/00; C07C43/164; C07C43/20; C07C43/23; C07C45/30; C07C45/46; C07C47/546; C07C49/215; C07C49/76; C07C49/86; C07C51/347; C07C57/44; C07C59/48; C07C59/64; C07C59/84; C07C59/90; C07C63/36; C07C65/24; C07C65/34; C07C65/40; C07C67/00; C07C69/618; C07C69/738; C07C69/76; C07C231/00; C07C231/02; C07C233/11; C07C233/65; C07C235/34; C07C235/66; C07C235/84; C07C239/00; (IPC1-7): C07C33/18; A61K7/00; A61K31/045; A61K31/085; A61K31/12; A61K31/16; A61K31/165; A61K31/19; A61K31/215; C07C29/143; C07C33/32; C07C41/18; C07C43/20; C07C45/46; C07C49/215; C07C51/347; C07C57/44; C07C59/48; C07C59/64; C07C59/84; C07C69/618; C07C69/76; C07C233/11; C07C233/65; C07C235/34; C07C235/66; C07C235/84
Attorney, Agent or Firm:
Shigeru Yagita (2 outside)