Title:
【発明の名称】呼吸器合胞体ウイルスのGタンパク質をコードする核酸ワクチン
Document Type and Number:
Japanese Patent JP2001512662
Kind Code:
A
Abstract:
Non-replicating vectors, such as plasmid vectors, containing a nucleotide sequence coding for a G protein of respiratory syncytial virus (RSV) and a promoter for such sequence, preferably a cytomegalovirus promoter, are described. Such vectors also may contain a further nucleotide sequence located adjacent to the RSV G protein encoding sequence to enhance the immunoprotective ability of the RSV G protein when expressed in vivo. Such non-replicating vectors may be used to immunize a host, including a human host, against RSV infection by administration thereto. Such non-replicating vectors also may be used to produce antibodies for detection of RSV infection in a sample.
Inventors:
Li, Kiaomao
Sambarla, Sayapurakesh
Crane, Michelle, H
Sambarla, Sayapurakesh
Crane, Michelle, H
Application Number:
JP2000503216A
Publication Date:
August 28, 2001
Filing Date:
July 16, 1998
Export Citation:
Assignee:
Connaught Laboratories Limited
International Classes:
A61K39/155; A61K48/00; C07K14/135; C07K16/10; C12N15/09; C12N15/45; C12P21/08; C12Q1/68; G01N33/53; (IPC1-7): C12N15/09; A61K48/00; C07K16/10; C12P21/08; C12Q1/68; G01N33/53
Attorney, Agent or Firm:
Nobuyuki Kaneda (2 others)