Title:
イミダゾリキノリン誘導体を用いた大腸疾病の治療又は結腸直腸癌腫の予防
Document Type and Number:
Japanese Patent JP2011509956
Kind Code:
A
Abstract:
The invention relates to treating colorectal polyps and precancercerous colorectal changes by topical administration of immunomodulating drugs of the imidazoquinoline family, such as imiquimod (1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine), resiquimod (4-amino-α,α-dimethyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinoline-1-ethanol), sotirimod (2-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-4-amine).
Inventors:
Joachim Mouse
Istvan Suzerny
Ursula Petzol
Istvan Suzerny
Ursula Petzol
Application Number:
JP2010542534A
Publication Date:
March 31, 2011
Filing Date:
December 23, 2008
Export Citation:
Assignee:
Meda AB
International Classes:
A61K31/4375; A61K9/08; A61K9/107; A61K31/4745; A61P35/00; C07D471/04; C07D471/14
Other References:
JPN6013027167; Ｎ Ｅｎｇｌ Ｊ Ｍｅｄ Ｖｏｌ．３４７，Ｎｏ．５, 2002, ｐ．３７４
JPN6013027168; Ｐｒｏｃｅｅｄ．Ｉｎｔ'ｌ．Ｓｙｍｐ．Ｃｏｎｔｒｏｌ．Ｒｅｌ．Ｂｉｏａｃｔ．Ｍａｔｅｒ．１９９７年，Ｎ２４，ｐ．３３７-３３８
JPN6013027165; ＣＡＮＣＥＲ ＲＥＳＥＡＲＣＨ Ｖｏｌ．５２, 1992, ｐ．３５２８-３５３３
JPN6013027166; ＤＩＳＥＡＳＥＳ ＯＦ ＴＨＥ ＣＯＬＯＮ＆ＲＥＣＴＵＭ Ｖｏｌ．５１，Ｎｏ．１, 200711, ｐ．２-９
JPN6013027168; Ｐｒｏｃｅｅｄ．Ｉｎｔ'ｌ．Ｓｙｍｐ．Ｃｏｎｔｒｏｌ．Ｒｅｌ．Ｂｉｏａｃｔ．Ｍａｔｅｒ．１９９７年，Ｎ２４，ｐ．３３７-３３８
JPN6013027165; ＣＡＮＣＥＲ ＲＥＳＥＡＲＣＨ Ｖｏｌ．５２, 1992, ｐ．３５２８-３５３３
JPN6013027166; ＤＩＳＥＡＳＥＳ ＯＦ ＴＨＥ ＣＯＬＯＮ＆ＲＥＣＴＵＭ Ｖｏｌ．５１，Ｎｏ．１, 200711, ｐ．２-９
Attorney, Agent or Firm:
Toshio Yano
Toshiomi Yamazaki
Takuya Kuno
Hiroshi Sugimoto
Takahashi
Kimihiro Hoshi
Hiroyasu Ninomiya
Einzel Felix-Reinhard
Toshiomi Yamazaki
Takuya Kuno
Hiroshi Sugimoto
Takahashi
Kimihiro Hoshi
Hiroyasu Ninomiya
Einzel Felix-Reinhard