Title:
マロニル-CoA脱炭酸酵素阻害剤を用いた疾患の治療法
Document Type and Number:
Japanese Patent JP4503232
Kind Code:
B2
Abstract:
The present invention relates to methods for the prophylaxis, management and treatment of certain diseases modulated by the inhibition of the enzyme malonyl-coenzyme A decarboxylase (malonyl-CoA decarboxylase, MCD) by the administration of a composition containing as an active ingredient a compound according to Formula I. In particular, the invention relates to methods for the prophylaxis, management and treatment of cardiovascular diseases, diabetes, acidosis, cancers, and obesity through the administration of a compound which inhibits malonyl-coenzyme A decarboxylase activity. The present invention also includes within its scope the novel process for the preparation of certain compounds
Inventors:
Argenius Thomas
Chen Me
Cheng Chi Fay
Haramura Masayuki
Fan uchin
Nathan alex
Tis sobouchy
Wallace David
Tsang Lin
Brown steve
Harmon Charles
Ropa Schuk Gary Dee.
Dick Jason Earl.
Chen Me
Cheng Chi Fay
Haramura Masayuki
Fan uchin
Nathan alex
Tis sobouchy
Wallace David
Tsang Lin
Brown steve
Harmon Charles
Ropa Schuk Gary Dee.
Dick Jason Earl.
Application Number:
JP2002559024A
Publication Date:
July 14, 2010
Filing Date:
January 22, 2002
Export Citation:
Assignee:
Chugai Pharmaceutical Co., Ltd.
International Classes:
C07D207/30; C07D295/18; A61K31/16; A61K31/165; A61K31/166; A61K31/167; A61K31/17; A61K31/175; A61K31/18; A61K31/195; A61K31/197; A61K31/198; A61K31/21; A61K31/215; A61K31/216; A61K31/22; A61K31/221; A61K31/223; A61K31/27; A61K31/275; A61K31/277; A61K31/341; A61K31/381; A61K31/40; A61K31/404; A61K31/41; A61K31/415; A61K31/416; A61K31/4164; A61K31/4172; A61K31/4178; A61K31/4188; A61K31/4196; A61K31/42; A61K31/421; A61K31/4245; A61K31/44; A61K31/4402; A61K31/4409; A61K31/4439; A61K31/444; A61K31/445; A61K31/4453; A61K31/451; A61K31/455; A61K31/495; A61K31/498; A61K31/5375; A61K31/5377; A61P3/04; A61P3/10; A61P3/12; A61P9/00; A61P9/04; A61P9/10; A61P35/00; A61P43/00; C07C33/46; C07C33/48; C07C215/24; C07C233/22; C07C257/22; C07C279/18; C07C307/10; C07C323/14; C07C335/18; C07D209/42; C07D211/14; C07D211/22; C07D213/40; C07D213/56; C07D213/70; C07D213/75; C07D213/81; C07D213/82; C07D231/06; C07D231/12; C07D231/14; C07D231/38; C07D231/40; C07D233/54; C07D233/64; C07D233/84; C07D233/90; C07D239/42; C07D241/24; C07D249/08; C07D257/04; C07D261/04; C07D261/08; C07D261/14; C07D261/18; C07D263/34; C07D271/06; C07D277/46; C07D277/48; C07D277/52; C07D285/135; C07D295/13; C07D295/194; C07D295/21; C07D295/215; C07D295/22; C07D295/28; C07D307/46; C07D307/52; C07D307/68; C07D333/24; C07D401/04; C07D401/12; C07D403/12; C07D405/12; C07D409/04; C07D413/06; C07D413/12; C07D417/12; C07D417/14; C07D487/08; C07D498/08; C07F9/24; C07F9/40; C07F9/6539; C07D285/12
Domestic Patent References:
| JP2007000000A | ||||
| JP2004527475A | ||||
| JP2004523542A |
Foreign References:
| WO2000054759A1 | ||||
| WO2001003705A1 |
Attorney, Agent or Firm:
Hatsushi Shimizu