Title:
キナーゼ阻害剤としてのトリフルオロメチル置換ベンズアミド
Document Type and Number:
Japanese Patent JP2008509187
Kind Code:
A
Abstract:
The invention relates to trifluoromethyl substituted benzamide compounds of the formula (I), pharmaceuticals comprising these compounds, their use as or for the manufacture of pharmaceuticals, particularly as inhibitors of protein kinases and/or the treatment of a condition, disorder or disease state mediated by a protein kinase activity and/or a proliferative disease, methods of treatment comprising administering the compounds, especially of therapeutic and prophylactic treatment, methods for the manufacture of the compounds and novel intermediates and partial steps for their synthesis.
Inventors:
Giorgio Caravatti
Pascal Fure
Patrizia Imbach
Georg Martini-Baron
Lawrence Brass Perez
Tao Shen
Pascal Fure
Patrizia Imbach
Georg Martini-Baron
Lawrence Brass Perez
Tao Shen
Application Number:
JP2007525252A
Publication Date:
March 27, 2008
Filing Date:
August 10, 2005
Export Citation:
Assignee:
NOVARTIS AG
International Classes:
C07D217/02; A61K31/428; A61K31/472; A61K31/496; A61K31/502; A61K31/517; A61K31/5377; A61P35/00; A61P43/00; C07D237/30; C07D239/74; C07D239/84; C07D277/62
Foreign References:
| WO2004010995A1 | 2004-02-05 |
Attorney, Agent or Firm:
Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi