Use as complex aromatic compounds and its dopamine D1 ligand

Title:

Use as complex aromatic compounds and its dopamine D1 ligand

Document Type and Number:

Japanese Patent JP6239149

Kind Code:

B2

Abstract:

The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), schizotypal personality disorder, cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), ADHD, Parkinson's disease, anxiety, and depression.

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Inventors:

David Lawrence Furman Gray
Ray Jean
Michael Aaron Brodney
Michael Eric Green
Chakra Pannie Sabraman Yum

Application Number:

JP2016564000A

Publication Date:

November 29, 2017

Filing Date:

April 09, 2015

Export Citation:

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Assignee:

Pfizer Inc.

International Classes:

C07D401/12; A61K31/501; A61K31/506; A61K31/513; A61P3/04; A61P3/06; A61P3/10; A61P7/10; A61P9/04; A61P9/10; A61P9/12; A61P15/10; A61P25/04; A61P25/06; A61P25/14; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/30; A61P27/02; A61P37/02; A61P43/00; C07D471/04

Domestic Patent References:

JP2013523652A
JP2009501164A
JP2010509392A
JP2012510991A
JP2013521286A

Foreign References:

CN102558147A

Attorney, Agent or Firm:

Noh four
Junko Miyazawa
Maki Sato
Tatsuta Miyuki

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