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Title:
自己免疫疾患治療のための乳酸菌の使用
Document Type and Number:
Japanese Patent JP5419455
Kind Code:
B2
Abstract:
The present technology relates to the use of at least one strain of probiotic bacteria selected from Lactobacillus for the manufacture of a medicament for the treatment and/or prevention of an autoimmune disease.

Inventors:
Allenfort Jean
Bergen Anna
Rusk Carroll
Wald Agnes
Agai Bake-Rabasani Shaharan
Application Number:
JP2008534491A
Publication Date:
February 19, 2014
Filing Date:
October 06, 2006
Export Citation:
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Assignee:
Probi AB
International Classes:
A61K35/74; A23L7/10; A23L29/00; A61K9/00; A61K9/08; A61K9/10; A61K9/14; A61K9/16; A61K9/20; A61K9/28; A61K9/48; A61K9/52; A61K35/747; A61P25/00; A61P37/02; C12N1/20
Domestic Patent References:
JP2004507265A
JP9002959A
Foreign References:
WO2004087893A1
WO2004067731A1
Other References:
Osman N, et al.,Modulation of the Effect of Dextran Sulfate Sodium-Induced Acute Colitis by the Administration of Different Probiotic Strains of Lactobacillus and Bifidobacterium,Digestive Diseases and Sciences,2004年 2月,Vol. 49, No. 2,p. 320-327
von der Weid T, et al.,Induction by a lactic acid bacterium of a population of CD4+ T cells with low proliferative capacity that produce transforming growth factor β and interleukin-10,Clinical and Diagnostic Laboratory Immunology,2001年 7月,Vol. 8, No. 4,p. 695-701
Kuruvilla AP, et al.,Protective effect of transforming growth factor beta 1 on experimental autoimmune diseases in mice,Proceedings of the National Academy of Sciences of the United States of America,1991年 4月 1日,Vol. 88, No. 7,p. 2918-2921
Beebe AM, et al.,The role of interleukin-10 in autoimmune disease: systemic lupus erythematosus (SLE) and multiple sclerosis (MS),Cytokine & Growth Factor Reviews,2002年 8月,Vol. 13, No. 4-5,p. 403-412
Reich K, et al.,Treatment of Psoriasis with Interleukin-10,Journal of Investigative Dermatology,1998年12月,Vol. 111, No. 6,p. 1235-1236
Pennline KJ, et al.,Recombinant Human IL-10 Prevents the Onset of Diabetes in the Nonobese Diabetic Mouse,Clinical Immunology and Immunopathology,1994年 5月,Vol. 71, No. 2,p. 169-175
Pathmakanthan S, et al.,Lactobacillus plantarum 299: beneficial in vitro immunomodulation in cells extracted from inflamed human colon,Journal of gastroenterology and hepatology,2004年 2月,Vol. 19, No. 2,p. 166-173
Schultz M, et al.,Lactobacillus plantarum 299V in the treatment and prevention of spontaneous colitis in interleukin-10-deficient mice,Inflammatory bowel diseases,2002年 3月,Vol. 8, No. 2,p. 71-80
Attorney, Agent or Firm:
Eiji Saegusa
Kenji Saito
Mutsuko Nakano
Masahito Hayashi