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Title:
USE OF PHYTOGLOBULIN FOR TREATMENT OF ARTERIOSCLEROSIS
Document Type and Number:
Japanese Patent JP2011184313
Kind Code:
A
Abstract:

To provide an oral medicine or a food composition for treatment of arteriosclerosis or an arteriosclerotic disease comprising a clinically effective amount of the whole part or a reactive part of phytoglobulin.

The phytoglobulin useful for treating or arresting atherosclerosis is obtained by dissolving a crude protein extracted from a raw material plant in 1M NaCl, fractionating the resultant solution using 30% ammonium sulfate, and dialyzing the resultant precipitate. The preferable example of the phytoglobulin is rice 19 kDa globulin.


Inventors:
SATO MASAHISA
IMAIZUMI KATSUMI
Application Number:
JP2010048403A
Publication Date:
September 22, 2011
Filing Date:
March 04, 2010
Export Citation:
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Assignee:
UNIV KYUSHU
International Classes:
A61K38/16; A23L1/30; A61K36/00; A61K36/899; A61P9/00; A61P9/10
Domestic Patent References:
JP2009280517A2009-12-03
JP2007051750A2007-03-01
JP2007517504A2007-07-05
Foreign References:
WO2002026243A12002-04-04
Other References:
JPN6014013551; J. Nutrition, 2004, Vol.134, No.3, pp.511-516
JPN6014013553; 化学関連支部合同九州大会・外国人研究者交流国際シンポジウム講演予稿集, 2008, Vol.45, p.318
JPN6014013556; アミノ酸研究, 2008, Vol.1, No.1, pp.53-54
JPN6014013558; Cereal Chemistry, 1982, Vol.59, No.3, pp.192-195
JPN6014051959; Gene, 1996, Vol.170, No.2, pp.223-226
JPN6014051960; Os05g0499100 [Oryza sativa Japonica Group], DATABASE NCBI Protein [online] Accession No. BAF17868 ,
Attorney, Agent or Firm:
Shinjiro Ono
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hisako Nozaki