Title:
Vaccine nanotechnology
Document Type and Number:
Japanese Patent JP6285374
Kind Code:
B2
Abstract:
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune response in T cells and/or in B cells, in some embodiments, comprising at least one immunomodulatory agent, and optionally comprising at least one targeting moiety and optionally at least one immunostimulatory agent. The invention provides pharmaceutical compositions comprising inventive vaccine nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive vaccine nanocarriers and pharmaceutical compositions thereof. The invention provides methods of prophylaxis and/or treatment of diseases, disorders, and conditions comprising administering at least one inventive vaccine nanocarrier to a subject in need thereof.
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Inventors:
Ulrich Har. von Andrian
Omidshi. Farocazad
Robert S. Langer
Tobias Junt
Elliott Ashley Morsman
Chang Liang Fan
Pamela bust
Mateo Ian Narcon
Frank alexis
Omidshi. Farocazad
Robert S. Langer
Tobias Junt
Elliott Ashley Morsman
Chang Liang Fan
Pamela bust
Mateo Ian Narcon
Frank alexis
Application Number:
JP2015025609A
Publication Date:
February 28, 2018
Filing Date:
February 12, 2015
Export Citation:
Assignee:
MASSACHUSETTS INSTITUTE OF TECHNOLOGY
PRESIDENT AND FELLOWS OFHARVARD COLLEGE
The Brigham And Women's Hospital Incorporated
ABBOTT LABORATORIES
PRESIDENT AND FELLOWS OFHARVARD COLLEGE
The Brigham And Women's Hospital Incorporated
ABBOTT LABORATORIES
International Classes:
A61K39/00; A61K9/127; A61K9/16; A61K39/02; A61K39/12; A61K39/39; A61K39/395; A61K45/00; A61K47/34; A61K47/60; A61K47/64; A61K47/68; A61P31/00; A61P35/00; A61P37/04
Other References:
Journal of Immunotherapy,2007年 6月,Vol.30,No.4,p378-395
Trends in Immunology,2006年,Vol.27,No.12,p573-579
Journal of Immunotherapy,2006年,Vol.29,No.2,p165-174
薬学雑誌,2007年 2月,Vol.127,No.2,p301-306
Journal of Translational Medicine,2007年 1月,Vol.5,No.5,p1-14
International Immunology,2006年,Vol.18,No.3,p425-434
臨床免疫,2006年,Vol.45,No.5,p483-490
Journal of Immunology,2007年 3月,Vol.178,No.5,p2979-2986
薬学雑誌,2007年 2月,Vol.127,No.2,p307-317
Drug Delivery System,2007年 5月,Vol.22,No.3,p289
Trends in Immunology,2006年,Vol.27,No.12,p573-579
Journal of Immunotherapy,2006年,Vol.29,No.2,p165-174
薬学雑誌,2007年 2月,Vol.127,No.2,p301-306
Journal of Translational Medicine,2007年 1月,Vol.5,No.5,p1-14
International Immunology,2006年,Vol.18,No.3,p425-434
臨床免疫,2006年,Vol.45,No.5,p483-490
Journal of Immunology,2007年 3月,Vol.178,No.5,p2979-2986
薬学雑誌,2007年 2月,Vol.127,No.2,p307-317
Drug Delivery System,2007年 5月,Vol.22,No.3,p289
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita
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