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Title:
VECTOR FOR CREATING NON-HUMAN ANIMAL IN WHICH GENE IS TRANSDUCED AND/OR DELETED
Document Type and Number:
Japanese Patent JP2002233374
Kind Code:
A
Abstract:

To provide a vector, for creating a transgenic non-human animal, having a function that permits site-specifically transducing only one copy of objective gene such as lethal gene, a function that permits controlling an expression time of the gene, and a function that permits early detection of an expression site of the gene, and a cell in which at least a part of the DNA of the vector is incorporated, a transgenic non-human animal created using the vector or cell.

This vector is constructed so as to contain a DNA prepared by linking a promoter gene, a DNA that has recombinase-recognizing sequence loxP and encodes fluorescent protein EGFP fused with SV40 poly A signal in both sides, and β-globin poly-A signal having a multi-cloning site for introducing an objective gene in the upstream side in this order.


Inventors:
SENOO MAKOTO
KAKIO SONOKO
Application Number:
JP2001030183A
Publication Date:
August 20, 2002
Filing Date:
February 06, 2001
Export Citation:
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Assignee:
JAPAN SCIENCE & TECH CORP
International Classes:
C12N5/10; C12N15/09; C12Q1/68; A01K67/027; (IPC1-7): C12N15/09; A01K67/027; C12N5/10
Attorney, Agent or Firm:
Hiroki Masaki