To provide a vehicle body frame for a saddle riding type four-wheel vehicle attaining light weight, capable of obtaining sufficient strength on a portion for supporting an engine and increasing degree of freedom of layout of a device mounted on a vehicle body.

The vehicle body frame 20 is provided with a lower part frame 21 extending in a longitudinal direction below the engine 11; and an upper part frame 25 arranged above the lower part frame 21. The lower part frame 21 has an engine support part 23 positioned below the engine 11 and supporting the engine 11 from below, and the engine support part 23 for supporting the engine at the lower part frame 21 is constituted by a material having larger coefficient of elasticity than the upper part frame 25.