Title:
The biomarker of brain damage
Document Type and Number:
Japanese Patent JP6071886
Kind Code:
B2
Abstract:
The present invention relates to the field of biomarkers. More specifically, the present invention relates to biomarkers useful in diagnosing brain injuries. Brain injury can include overt or traumatic brain injury, as well as subclinical brain injury (SCI). In one embodiment, a method for diagnosing SCI in a patient comprises (a) collecting a sample from the patient; (b) measuring the levels of a panel of biomarkers in the sample collected from the patient, wherein the panel of biomarkers comprises ASTN1, BAI3, CNDP1, ERMIN, GFAP, GRM3, KLH32, MAGE2, NRG3, NRGN, OMG, SLC39A12, RTN1, and MT3; and (c) comparing the levels of the panel of biomarkers with predefined levels of the same panel of biomarkers that correlate to a patient having SCI and predefined levels of the same panel of biomarkers that correlate to a patient not having SCI, wherein a correlation to one of the predefined levels provides the diagnosis.
Inventors:
Everett Alan Dale
Casera James Francis
Van ake jennifer
Casera James Francis
Van ake jennifer
Application Number:
JP2013534031A
Publication Date:
February 01, 2017
Filing Date:
October 14, 2011
Export Citation:
Assignee:
The Johns Hopkins University
International Classes:
G01N33/68; C07K14/435; C07K16/18; G01N33/53; G01N33/72
Domestic Patent References:
| JP2008504032A |
Foreign References:
| WO2010019553A2 | ||||
| GB1008541A |
Attorney, Agent or Firm:
Masahiro Abe
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