Title:
二重特異性抗ＣＤ３７抗体、モノクローナル抗ＣＤ３７抗体、およびそれらの使用方法
Document Type and Number:
Japanese Patent JP7330942
Kind Code:
B2
Abstract:
CD37-specific bispecific antibody molecules binding to different epitopes of the human CD37 antigen which bispecific antibody molecules have enhanced Fc-Fc interactions upon binding to CD37 on the cell surface. The invention also relates to the monoclonal parental antibodies from which the first or the second binding region of the bispecific antibody molecules is obtained. The invention also relates to pharmaceutical compositions containing these molecules and the treatment of cancer and other diseases using these compositions.
Inventors:
Austindy Simone
Bühlskens Frank
Blaze Esther
Van den Brink Edward
Hollen Stain Andreas
Overdike Maraier
Lindolfer Margaret
Taylor ronald
Palen Paul
Van der Horst Hilma
E.D. Shamro Martinet
Mutis Tuna
Bühlskens Frank
Blaze Esther
Van den Brink Edward
Hollen Stain Andreas
Overdike Maraier
Lindolfer Margaret
Taylor ronald
Palen Paul
Van der Horst Hilma
E.D. Shamro Martinet
Mutis Tuna
Application Number:
JP2020503365A
Publication Date:
August 22, 2023
Filing Date:
April 03, 2018
Export Citation:
Assignee:
Gemmab Holding B.V.
International Classes:
C12N15/13; A61K39/395; A61P35/00; A61P35/02; A61P37/06; A61P37/08; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/63; G01N33/53; G01N33/531
Domestic Patent References:
| JP2016509476A | ||||
| JP2013524777A | ||||
| JP2009539413A |
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Shun Jinbe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Shun Jinbe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto
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