Title:
BISPECIFIC ANTIBODY
Document Type and Number:
Japanese Patent JP2023100938
Kind Code:
A
Abstract:
To provide a novel antibody that can be used as an anti-tumor agent and an anti-tumor agent that comprises, as an active ingredient, a molecule containing such an antibody.SOLUTION: An antibody or a binding fragment thereof comprises: a heavy chain CDRH1 consisting of a specific amino acid sequence, a heavy chain CDRH2 consisting of a specific amino acid sequence, a heavy chain CDRH3 consisting of a specific amino acid sequence, a light chain CDRL1 consisting of a specific amino acid sequence or a light chain CDRL1 consisting of an amino acid sequence derived from the specific amino acid sequence in which amino acid 7 is W and/or amino acid 8 is K, a light chain CDRL2 consisting of a specific amino acid sequence, and a light chain CDRL3 consisting of a specific amino acid sequence or a light chain CDRL3 consisting of an amino acid sequence derived from the specific amino acid sequence in which amino acid 2 is A or S.SELECTED DRAWING: None
Inventors:
SHUKU HIROSHI
AKAHORI YASUSHI
TANAKA KENTO
YATSU AYAKA
ICHIKAWA JUNYA
OTSUKA TOSHIAKI
KAMITSUMA SHIHO
HASHIMOTO RYUJI
NAKAYAMA MAKIKO
SHINOZAKI NAOYA
NAKAMURA KENSUKE
WATANABE ICHIRO
FURUZONO SHINJI
AKAHORI YASUSHI
TANAKA KENTO
YATSU AYAKA
ICHIKAWA JUNYA
OTSUKA TOSHIAKI
KAMITSUMA SHIHO
HASHIMOTO RYUJI
NAKAYAMA MAKIKO
SHINOZAKI NAOYA
NAKAMURA KENSUKE
WATANABE ICHIRO
FURUZONO SHINJI
Application Number:
JP2023078244A
Publication Date:
July 19, 2023
Filing Date:
May 11, 2023
Export Citation:
Assignee:
UNIV MIE
DAIICHI SANKYO CO LTD
DAIICHI SANKYO CO LTD
International Classes:
C12N15/13; A61K31/7088; A61K35/12; A61K39/395; A61K45/00; A61K48/00; A61P35/00; A61P35/02; C07K16/18; C07K16/28; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/62; C12N15/63; C12P21/08
Attorney, Agent or Firm:
Patent Attorney Corporation Hiraki International Patent Office