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Title:
拮抗的抗原結合タンパク質
Document Type and Number:
Japanese Patent JP7430924
Kind Code:
B2
Abstract:
The present invention relates to antagonistic antigen binding proteins, a nucleic acid encoding the antagonistic binding protein, a recombinant expression vector comprising the nucleic acid molecule, a host cell comprising the vector, a method of making the antagonistic antigen binding protein, an antagonistic binding protein produced by the method and a pharmaceutical composition comprising the antagonistic binding protein, the nucleic acid or the vector. The present invention further relates to a kit comprising the pharmaceutical composition and use of the antagonistic binding protein in the treatment of cancer and/or chronic infectious diseases.

Inventors:
Nicosia, Alfred
Zambrano, Nicola
Sasso, Emanuele
de lorenzo, claudia
Application Number:
JP2021500349A
Publication Date:
February 14, 2024
Filing Date:
March 22, 2019
Export Citation:
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Assignee:
Kayles Age
International Classes:
C12N15/13; A61K39/395; A61P31/00; A61P31/04; A61P31/14; A61P31/18; A61P31/20; A61P31/22; A61P35/00; A61P43/00; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/63; C12P21/08
Domestic Patent References:
JP2016521692A
JP2017505125A
JP2016523265A
Foreign References:
WO2017025051A1
WO2016020856A1
Attorney, Agent or Firm:
Takashi Shoji
Yuriko Sukenobu
Takuya Osugi
Hirata Midori
Akira Shoji