A constituent and a method relevant to a protein A (SpA) antibody as an enhancer of immunoreaction

Title:

A constituent and a method relevant to a protein A (SpA) antibody as an enhancer of immunoreaction

Document Type and Number:

Japanese Patent JP6042574

Kind Code:

B2

Abstract:

The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant or an antibody directed thereto.

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Inventors:

Schnee Wind Olaf
Chen Alice
Misiacus Dominique M.
Kim fan

Application Number:

JP2016074958A

Publication Date:

December 14, 2016

Filing Date:

April 04, 2016

Export Citation:

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Assignee:

KONINKLIJKE PHILIPS N.V.

International Classes:

A61K39/395; A61K38/00; A61K39/02; A61K39/085; A61P31/04; A61P37/04; A61P43/00

Domestic Patent References:

JP2008518947A
JP2005520853A

Other References:

Journal of Experimental Medicine,2008年,Vol.205,No.2,p287-294
Infection and Immunity,1996年,Vol.64,No.5,p1839-1841
Proc.Natl.Acad.Sci.USA,2006年,Vol.103,No.45,p16942-16947
Microbes and Infection,2005年,Vol.7,No.15,p1501-1511
Journal of Dairy Science,1985年,Vol.68,No.3,p.726-731

Attorney, Agent or Firm:

Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto

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