Title:
Cyclopropylamine compound as a histone demethylase inhibitor
Document Type and Number:
Japanese Patent JP6320570
Kind Code:
B2
Abstract:
The present disclosure relates to cyclopropyl compounds of general formula (I), wherein R1, and R2 are as defined in the specification. The present application also relates to pharmaceutical compositions containing such compounds and to their use in therapy.
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Inventors:
Paola Vianello
Mario Varaj
Ciro Mercurio
Anna Kappa
Giuseppe Meloni
Manuela villa
Antonello Mai
Sergio Valente
Mario Varaj
Ciro Mercurio
Anna Kappa
Giuseppe Meloni
Manuela villa
Antonello Mai
Sergio Valente
Application Number:
JP2016570280A
Publication Date:
May 09, 2018
Filing Date:
May 29, 2015
Export Citation:
Assignee:
Jeo-Istituto Europeo di Oncologia Esse Elle Elle
International Classes:
C07D211/34; A61K31/421; A61K31/4453; A61K31/451; A61K31/495; A61K31/5375; A61K45/00; A61P1/16; A61P3/04; A61P11/00; A61P25/00; A61P31/04; A61P35/00; A61P35/02; A61P43/00; C07D263/22; C07D295/14
Domestic Patent References:
JP2013525318A |
Foreign References:
WO2013022047A1 |
Other References:
Jounral of Medicinal Chemistry,2014年,57,pp.42-55
J. Am. Chem. Soc.,2010年,132(19),pp.6827-6833
J. Am. Chem. Soc.,2010年,132(19),pp.6827-6833
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mitsuhiro
Tatsuhiko Abe
Shinya Mitsuhiro
Tatsuhiko Abe
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