Title:
hCG液体製剤
Document Type and Number:
Japanese Patent JP4165718
Kind Code:
B2
Abstract:
A liq. pharmaceutical compsn. comprises human chorionic gonadotropin (hCG) and a stabilising amt. of a polyalcohol or a non-reducing sugar. The polyalcohol is mannitol. The non-reducing sugar is sucrose. The hCG is recombinant. The soln. is a buffered aq. soln. selected from acetate, succinate and phosphate buffer. The buffer soln. is at pH 7 and is a 0.01M soln. The compsn. esp. comprises 1000-40000 IU/ml of hCG and 10-180 mg/l of mannitol in a 0.01M phosphate buffer at pH 7.00.
Inventors:
Samari Tani, Fabrizio
Natale, Patrizia
Natale, Patrizia
Application Number:
JP52800396A
Publication Date:
October 15, 2008
Filing Date:
March 21, 1995
Export Citation:
Assignee:
Laboratore Serono Society Anonym
International Classes:
A61K38/24; A61K9/00; A61K47/24; A61K9/08; A61K47/26
Domestic Patent References:
| JP3255036A | ||||
| JP6135852A | ||||
| JP6508156A | ||||
| JP3041033A | ||||
| JP5025058A | ||||
| JP3500882A |
Foreign References:
| WO1993011788A1 |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Kazuhiro Nakamura
Ikeda Tatsunori
Shintaro Koike
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Kazuhiro Nakamura
Ikeda Tatsunori
Shintaro Koike