Title:
The human antibody to human TNF Mr. ligand 1A (TL1A)
Document Type and Number:
Japanese Patent JP6076911
Kind Code:
B2
Abstract:
A fully human antibody or antigen-binding fragment of a human antibody that specifically binds and inhibits human TNF-like ligand 1A (hTL1A) is provided. The human anti-hTL1A antibodies are useful in treating diseases or disorders associated with TL1A, such as inflammatory diseases or disorders, e.g., inflammatory bowel diseases, including ulcerative colitis and Crohn's disease, rheumatoid arthritis, and the like; autoimmune diseases or disorders, such as multiple sclerosis, diabetes, and the like; and allergic reactions, such as asthma and allergic lung inflammation.
Inventors:
Brendan Jay Clason
Dimitris Sukosu
Dimitris Sukosu
Application Number:
JP2013537924A
Publication Date:
February 08, 2017
Filing Date:
November 08, 2011
Export Citation:
Assignee:
REGENERON PHARMACEUTICALS, INC.
International Classes:
C07K16/24; A61K39/395; A61P1/00; A61P1/04; A61P3/10; A61P11/00; A61P11/06; A61P25/00; A61P29/00; A61P37/06; A61P37/08; C12N15/09; C12P21/08
Domestic Patent References:
| JP2003506088A |
Foreign References:
| WO2009064854A1 |
Other References:
GASTROENTEROLOGY,2008年,Vol.135, No.2,p.552-567, 567.e1-e2
J. Exp. Med.,2008年,Vol.205, No.11,p.2457-2464
消化器内科,2010年10月28日,Vol.51, No.4,p.353-360
J. Exp. Med.,2008年,Vol.205, No.11,p.2457-2464
消化器内科,2010年10月28日,Vol.51, No.4,p.353-360
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mitsuhiro
Tatsuhiko Abe
Shinya Mitsuhiro
Tatsuhiko Abe
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