An immunogenicity constituent and a method for treating neuropathy - GlaxoSmithKline Biologicals Society Anonymous

Title:

An immunogenicity constituent and a method for treating neuropathy

Document Type and Number:

Japanese Patent JP6093304

Kind Code:

B2

Abstract:

Compositions and methods for preventing and/or reducing amyloid deposition in a subject comprising treatment of a subject with a composition comprising a TLR4 agonist free of endotoxin are provided. Also provided is a TLR4 agonist free of endotoxin for preventing and/or reducing Alzheimer's disease. Pharmaceutical compositions consisting of, or consisting essentially of, an aminoalkyl glucosaminide phosphate, 3D-MPL, AS01 B or an AGP in combination with an oil in water emulsion are also provided.

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Inventors:

Halle, Maxim
Laroque, Daniel
Remy Parmentier
Priors, Jean-Paul
Tribute-Jovar, Pascal

Application Number:

JP2013535445A

Publication Date:

March 08, 2017

Filing Date:

October 27, 2011

Export Citation:

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Assignee:

GlaxoSmithKline Biologicals Society Anonymous

International Classes:

A61K31/715; A61K9/127; A61P25/28

Domestic Patent References:

JP2009519309A

Foreign References:

WO2010075545A1

Other References:

Brain,2006年,129,3006-19
FASEB J,2002年,16(6),601-3
Mediators Inflamm,2010年 8月,2010,1-12,Article ID 497987
Brain Res Rev,2009年,59(2),278-92

Attorney, Agent or Firm:

Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka

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