Title:
インターロイキン−１受容体アンタゴニストを送達するための方法および組成物
Document Type and Number:
Japanese Patent JP5551250
Kind Code:
B2
Abstract:
Methods and compositions generating and using an interleukin-1 receptor antagonist (IL-1ra)-rich solution. Methods for generating and isolating interleukin-1 receptor antagonist include incubating adipose tissue and/or adipocytes with polyacrylamide beads to produce interleukin-1 receptor antagonist. The interleukin-1 receptor antagonist is isolated from the polyacrylamide beads to obtain the solution rich in interleukin-1 receptor antagonist. Methods for treating a site of inflammation in a patient include administering to the site of inflammation the solution rich in interleukin-1 receptor antagonist.
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Inventors:
Joel, See. Higgins
Jennifer, E. ウッデル‐メイ
Jasey, オエップナー
Jennifer, E. ウッデル‐メイ
Jasey, オエップナー
Application Number:
JP2012526988A
Publication Date:
July 16, 2014
Filing Date:
August 26, 2010
Export Citation:
Assignee:
Biomet, biologics, the Limited, liability, companies BIOMET BIOLOGICS and LLC
International Classes:
C12P21/02; A61K33/06; A61K38/00; A61K38/43; A61K38/48; A61K38/55; A61P19/02; A61P29/00; A61P43/00; C12R1/91
Attorney, Agent or Firm:
Katsunuma Hirohito
Yukitaka Nakamura
Nobutaka Yokota
Takehiro Ito
Omori Michiko
Yukitaka Nakamura
Nobutaka Yokota
Takehiro Ito
Omori Michiko