Title:
o-二置換芳香族化合物の製造方法
Document Type and Number:
Japanese Patent JP5061632
Kind Code:
B2
Abstract:
A method of producing an o-disubstituted aromatic compound, containing: continuously conducting at least the following steps (a) to (d): (a) a step of mono-lithiating one halogen atom of an o-dihaloaromatic compound, using a first microreactor; (b) a step of making the thus-obtained monolithiated product to react with an electrophilic compound, using a second microreactor, to obtain a monosubstituted-monohaloaromatic compound; (c) a step of lithiating the other halogen atom of the o-dihaloaromatic compound, using a third microreactor; and (d) a step of making the thus-obtained lithiated product successively to react with an electrophilic compound, using a forth microreactor.
Inventors:
Junichi Yoshida
Aiichiro Nagaki
Toshiki Nogami
Aiichiro Nagaki
Toshiki Nogami
Application Number:
JP2007031346A
Publication Date:
October 31, 2012
Filing Date:
February 09, 2007
Export Citation:
Assignee:
Wako Pure Chemical Industries, Ltd.
International Classes:
C07C29/38; C07C33/24; C07F7/08; C07F7/22
Domestic Patent References:
| JP2006241065A | ||||
| JP2006193483A | ||||
| JP2005505628A |
Foreign References:
| US5904424 |
Attorney, Agent or Firm:
Toshizo Iida
Wataru Sasaki
Naosuke Miyamae
Wataru Sasaki
Naosuke Miyamae