Title:
ヒト子宮頸癌抑制タンパク質、そのタンパク質をコードするポリヌクレオチド、そのポリヌクレオチドで形質転換された細胞およびその発現ベクターを用いて癌細胞の増殖を抑制する方法
Document Type and Number:
Japanese Patent JP3749182
Kind Code:
B2
Abstract:
The present invention provides a human tumor suppressor protein having the amino acid sequence of SEQ ID NO: 2; a polynucleotide encoding the tumor suppressor protein; an expression vector containing the polynucleotide; a microorganism or animal cell transformed with the expression vector; a method for suppressing proliferation of a cancer cell which comprises introducing the expression vector into a cancer cell to induce apoptosis thereof; and a pharmaceutical composition for preventing or treating cancer which comprises a therapeutically effective amount of the polynucleotide and a pharmaceutically acceptable carrier.
Inventors:
Kim, Jin Woo
Application Number:
JP2001578474A
Publication Date:
February 22, 2006
Filing Date:
December 04, 2000
Export Citation:
Assignee:
Kim, Jin Woo
International Classes:
C07K14/47; C12N15/09; A61K38/00; A61K48/00; A61P35/00; A61P43/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/12
Foreign References:
| US5843773 |
Other References:
Gerhard, D. S. et al,"zt13g11.r1 NCI_CGAP_GCB1 Homo sapiens cDNA clone IMAGE",Genbank [online], ,Accession No.AA282293
INTERNATIONAL Jouranl of Cancer. 2002, Vol.97, No.6, p.780-786
INTERNATIONAL Jouranl of Cancer. 2002, Vol.97, No.6, p.780-786
Attorney, Agent or Firm:
Aoyama Aoi
Osamu Kawamiya
Kyousei Tamura
Misako Ohsaku
Osamu Kawamiya
Kyousei Tamura
Misako Ohsaku