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Title:
The monoclonal antibody to Claudin 18 for the medical treatment of cancer
Document Type and Number:
Japanese Patent JP6261650
Kind Code:
B2
Abstract:
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.

Inventors:
Sahin, Uguru
Thulech, Ezrem
Usener, Dark
Fritz, Stefan
Uchelek, Christoph
Brandenburg, Gunda
Geppert, Harald Gerhard
Sheroder, Anya Christina
Teal, Philip
Application Number:
JP2016098892A
Publication Date:
January 17, 2018
Filing Date:
May 17, 2016
Export Citation:
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Assignee:
Ganymed Pharmaceuticals Game Behr
International Classes:
C07K16/30; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12P21/08
Foreign References:
WO2004047863A1
WO2004029207A1
Other References:
Shinkawa T et al,The Journal of Biological Chemistry,2003年 1月31日,Vol. 278, No. 5,p. 3466-3473
Attorney, Agent or Firm:
Shinji Hayami



 
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