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Title:
The neutralization antibody to main outside toxins TcdA and TcdB of clostridium Difficile
Document Type and Number:
Japanese Patent JP6152107
Kind Code:
B2
Abstract:
This present invention describes the derivation and selection of antibodies capable of neutralising the major exotox-in; TcdA of Clostridium difficile. The invention also describes novel neutralisation and antigen binding properties of in-dividual Mabs and mixtures thereof.

Inventors:
Humphreys, David Paul
Lightwood, Daniel John
Tyson, Kelly Louise
Knight, David Edward Ormond
Herve, Carine Jeannine Madeleine
Compson, Joanne Elizabeth
Page, Matthew John Timothy
Payne, Andrew Charles
Fisher, Nikola Louise
Mackenzie, Brendon
COX, Matthew
Application Number:
JP2014530307A
Publication Date:
June 21, 2017
Filing Date:
September 10, 2012
Export Citation:
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Assignee:
Yusebe Pharma Societe Anonym
International Classes:
C07K16/12; A61K39/08; A61K39/395; A61P31/04
Domestic Patent References:
JP2007533330A
JP2006515837A
Foreign References:
WO2009155724A1
Other References:
Infection and Immunity,2006年,Vol.74, No.11,p.6339-6347
Attorney, Agent or Firm:
Asamura patent office