Title:
COPDおよび喘息の処置に有用な新規1-ベンジル-4-ピペリジンアミン
Document Type and Number:
Japanese Patent JP2009514853
Kind Code:
A
Abstract:
The invention provides 1-benzyl-4-piperidinamines of the general formula (I), processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are useful in the treatment of respiratory diseases such as chronic obstructive pulmonary disease and asthma. The compounds are inhibitors of the CCR1 receptor.
Inventors:
Martin Hemmelring
Nafsal Hossain
Svetlana Ivanova
Tessfaredet Mussi
Igor Shamovsky
Author Schaholm Timmen
Nafsal Hossain
Svetlana Ivanova
Tessfaredet Mussi
Igor Shamovsky
Author Schaholm Timmen
Application Number:
JP2008538845A
Publication Date:
April 09, 2009
Filing Date:
October 31, 2006
Export Citation:
Assignee:
ASTRAZENECA AKTIEBOLAG
International Classes:
A61K31/4468; C07D211/58; A61K31/454; A61P1/02; A61P1/04; A61P1/16; A61P3/10; A61P7/00; A61P11/00; A61P11/02; A61P11/06; A61P13/02; A61P13/08; A61P13/10; A61P15/08; A61P15/10; A61P17/00; A61P17/04; A61P17/06; A61P17/14; A61P19/02; A61P19/04; A61P19/06; A61P19/08; A61P25/00; A61P25/04; A61P25/06; A61P25/28; A61P27/02; A61P27/14; A61P29/00; A61P31/06; A61P31/08; A61P31/10; A61P31/12; A61P31/16; A61P31/18; A61P35/00; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07D401/12
Attorney, Agent or Firm:
Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Takuji Yamada
Mitsutaka Iwasaki