Title:
ＣＤ４０およびＦＡＰに特異的に結合することができる新規な二重特異性抗原結合分子
Document Type and Number:
Japanese Patent JP7288943
Kind Code:
B2
Abstract:
The invention relates to novel bispecific antigen binding molecules, comprising (a) at least one antigen binding domain capable of specific binding to CD40, and (b) at least one antigen binding domain capable of specific binding to a target cell antigen, in particular Fibroblast Activation Protein (FAP), and to methods of producing these molecules and to methods of using the same.
Inventors:
Bruenker, Peter
Bujotzek, Alexander
Dur, Harald
Georges, Ghee
Klein, Christian
Leclerc, Stephane
Rap, Moritz
Sam, Eva Carina
Trump Feller, Christine
Umagna, Pablo
Bujotzek, Alexander
Dur, Harald
Georges, Ghee
Klein, Christian
Leclerc, Stephane
Rap, Moritz
Sam, Eva Carina
Trump Feller, Christine
Umagna, Pablo
Application Number:
JP2021165225A
Publication Date:
June 08, 2023
Filing Date:
October 07, 2021
Export Citation:
Assignee:
Ef Hoffman-La Roche Akchengezel Shaft
International Classes:
C07K16/46; A61K39/395; A61P31/00; A61P35/00; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/13; C12N15/63; C12P21/08
Domestic Patent References:
| JP2016529215A |
Other References:
Journal of Immunology,2009年,Vol.183, pp.1851-1861
Attorney, Agent or Firm:
Sonoda & Kobayashi Patent Attorneys Corporation
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