Title:
μ－オピオイド受容体アゴニスト及びその調製方法及び医療分野におけるその使用
Document Type and Number:
Japanese Patent JP7019035
Kind Code:
B2
Abstract:
Disclosed are a class of µ-opioid receptor agonists and a preparation method therefor and the use thereof in the field of medicine, belonging to the field of medicinal chemistry. The µ-opioid receptor agonists significantly increase the selectivity for a G protein signaling pathway, and not only can exhibit excellent pharmacodynamic effects, but also significantly improve safety.
Inventors:
許▲しん▼
張▲ぜん▼
Lee Yun Fei
Zhang Tateaki
Guo Feng Ying
Jiang Qingyun
Li,Dong-Sheng
Zhang Linli
Song Nishiki Inui
Liu Lee
Liu Qiang
Lim Soo Jung
Royal art
Kuzuken
張▲ぜん▼
Lee Yun Fei
Zhang Tateaki
Guo Feng Ying
Jiang Qingyun
Li,Dong-Sheng
Zhang Linli
Song Nishiki Inui
Liu Lee
Liu Qiang
Lim Soo Jung
Royal art
Kuzuken
Application Number:
JP2020515923A
Publication Date:
February 14, 2022
Filing Date:
September 17, 2018
Export Citation:
Assignee:
SHANGHAI SYNERGY PHARMACEUTICAL SCIENCES CO., LTD
International Classes:
C07D405/04; A61K9/08; A61K31/4433; A61K31/4436; A61K31/4439; A61K31/444; A61K31/4725; A61K47/10; A61P1/04; A61P1/08; A61P1/12; A61P11/00; A61P13/02; A61P15/00; A61P25/00; A61P25/04; A61P25/06; A61P25/18; A61P25/30; A61P25/32; A61P29/00; A61P37/02; A61P43/00; C07D405/14; C07D409/14; C07D495/04
Domestic Patent References:
| JP2014508811A |
Foreign References:
| WO2017106306A1 | ||||
| WO2017106547A1 | ||||
| CN106588899A |
Attorney, Agent or Firm:
Sonoda/Kobayashi Patent Business Corporation