Title:
The ornamentation factor of the ATP-joint cassette transporter
Document Type and Number:
Japanese Patent JP6072056
Kind Code:
B2
Abstract:
Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
Inventors:
Adam Earl Looker
Benjamin Joseph Littler
Anusya choudhuri
Christian El Harrison
Rabicanto Berri
Michael pee ryan
Li Zhong Jian
Eduardo Luz-Lusys
Benjamin Joseph Littler
Anusya choudhuri
Christian El Harrison
Rabicanto Berri
Michael pee ryan
Li Zhong Jian
Eduardo Luz-Lusys
Application Number:
JP2014541272A
Publication Date:
February 01, 2017
Filing Date:
November 08, 2012
Export Citation:
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED
International Classes:
A61K31/553; C07D498/04; A61K45/00; A61P3/06; A61P3/10; A61P5/14; A61P7/10; A61P7/12; A61P11/00; A61P13/02; A61P13/12; A61P17/00; A61P19/08; A61P21/02; A61P21/04; A61P25/00; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P35/00; A61P37/02; A61P43/00; C12Q1/02; G01N33/53; G01N33/566
Domestic Patent References:
| JP2009533351A |
Foreign References:
| US20090131492 | ||||
| WO2010053471A1 | ||||
| WO2011133751A1 | ||||
| WO2011133951A1 |
Attorney, Agent or Firm:
Takuji Yamada
Aoyama Aoi
Michiko Matsutani
Yasushi Ochiai
Aoyama Aoi
Michiko Matsutani
Yasushi Ochiai