Title:
The vaccine of a Clostridiumdifficile toxin base
Document Type and Number:
Japanese Patent JP6084631
Kind Code:
B2
Abstract:
The present invention relates to recombinant fragments of C. difficile TcdA and TcdB that may be used in the development of vaccines against C. difficile associated disease. More particularly it relates to combinations comprising a ToxB-GT antigen and a TcdA antigen or a ToxA-GT antigen and a TcdB antigen.
Inventors:
Scarselli, Maria
Pizza, Maria Grazia
Revuzzi, Rosana
Arico, Maria
Martinelli, Manuele
Dooose, Gillian
Pizza, Maria Grazia
Revuzzi, Rosana
Arico, Maria
Martinelli, Manuele
Dooose, Gillian
Application Number:
JP2014545387A
Publication Date:
February 22, 2017
Filing Date:
December 07, 2012
Export Citation:
Assignee:
Novartis Age
International Classes:
A61K39/08; A61K39/00; A61K39/39; A61P1/00; A61P31/04; A61P37/04; A61P43/00
Foreign References:
| WO2011068953A1 | ||||
| WO2011130650A1 |
Other References:
Infection and Immunity,2006年,74(11),p.6339-6347
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita