Title:
7H-PYRROLOPYRIMIDINE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO2005077951
Kind Code:
A3
Abstract:
The invention relates to 7H-pyrrolo[2,3-d]pyrimidine derivatives of formula (I), wherein the symbols and substituents are as defined in the description, to processes for the preparation thereof, to pharmaceutical compositions comprising such derivatives and to the use of such derivatives - alone or in combination with one or more other pharmaceutically active compounds - for the preparation of pharmaceutical compositions for the treatment especially of a proliferative disease, such as a tumour.
Inventors:
CARAVATTI GIORGIO (CH)
VAUPEL ANDREA (CH)
VAUPEL ANDREA (CH)
Application Number:
PCT/EP2005/001635
Publication Date:
March 02, 2006
Filing Date:
February 17, 2005
Export Citation:
Assignee:
NOVARTIS AG (CH)
NOVARTIS PHARMA GMBH (AT)
CARAVATTI GIORGIO (CH)
VAUPEL ANDREA (CH)
NOVARTIS PHARMA GMBH (AT)
CARAVATTI GIORGIO (CH)
VAUPEL ANDREA (CH)
International Classes:
C07D487/04; (IPC1-7): C07D487/04; A61K31/519; A61P35/00
Domestic Patent References:
| WO2005075460A2 | 2005-08-18 | |||
| WO2005067546A2 | 2005-07-28 | |||
| WO2003037897A2 | 2003-05-08 | |||
| WO2003013541A1 | 2003-02-20 | |||
| WO1999065909A1 | 1999-12-23 | |||
| WO1998007726A1 | 1998-02-26 |
Foreign References:
| EP0888349B1 | 2002-05-22 |
Other References:
CARAVATTI G ET AL: "PYRROLOÄ2,3-ÜPYRIMIDINE AND PYRAZOLOÄ3,4-DÜPYRIMIDINE DERIVATIVES AS SELECTIVE INHIBITORS OF THE EGF RECEPTOR TYROSINE KINASE", ACS SYMPOSIUM SERIES, WASHINGTON, DC, US, vol. 796, 2001, pages 231 - 244, XP009002867, ISSN: 0097-6156
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