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Title:
ACYLAMIDE COMPOUND WITH ACTION OF ENHANCING SECRETION OF ADIPONECTIN OR INDUCING ADIPONECTIN
Document Type and Number:
WIPO Patent Application WO/2006/082978
Kind Code:
A1
Abstract:
It is intended to provide an acylamide compound represented by the following formula (1), a pro-drug thereof or a pharmaceutically acceptable salt thereof and an adiponectin inducer, an adiponectin secretion enhancer, a metabolic syndrome therapeutic agent, a hypoadiponectinemia therapeutic agent, a hyperlipemia therapeutic agent, a diabetes preventive/therapeutic agent, an impaired glucose tolerance ameliorating agent, an insulin sensitizer, an insulin sensitivity enhancer, a hypertension therapeutic agent, an angiopathy preventive/therapeutic agent or an anti-inflammatory agent, a hepatitis therapeutic agent, a steatosis therapeutic agent, a liver fibrosis therapeutic agent, a hepatic cirrhosis therapeutic agent, a preventive/therapeutic agent for non-alcoholic/nonviral steatohepatitis (NASH) or non-alcoholic/nonviral fatty liver disease (NAFLD) or an obesity therapeutic agent that contains any of these compounds as an active ingredient.

Inventors:
MAEZONO KATSUMI (JP)
YOSHIMURA TOSHIHIKO (JP)
ISHIDA NOZOMU (JP)
FUKUCHI NAOYUKI (JP)
HATANAKA TOSHIHIRO (JP)
IKEHARA OSAMU (JP)
KAWATO YAYOI (JP)
TANAKA HIDEYUKI (JP)
Application Number:
PCT/JP2006/302058
Publication Date:
August 10, 2006
Filing Date:
February 07, 2006
Export Citation:
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Assignee:
AJINOMOTO KK (JP)
MAEZONO KATSUMI (JP)
YOSHIMURA TOSHIHIKO (JP)
ISHIDA NOZOMU (JP)
FUKUCHI NAOYUKI (JP)
HATANAKA TOSHIHIRO (JP)
IKEHARA OSAMU (JP)
KAWATO YAYOI (JP)
TANAKA HIDEYUKI (JP)
International Classes:
C07C233/47; A23L1/30; A23L2/00; A61K31/198; C07C233/49; C07C233/52; C07C237/22; C07C323/59
Foreign References:
JP2001187769A2001-07-10
JPH09503295A1997-03-31
JPH05132454A1993-05-28
Attorney, Agent or Firm:
Kumakura, Yoshio (Shin-Tokyo Bldg. 3-1, Marunouchi 3-chom, Chiyoda-ku Tokyo, JP)
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