AKT-3 NUCLEIC ACIDS, POLYPEPTIDES, AND USES THEREOF

Title:

AKT-3 NUCLEIC ACIDS, POLYPEPTIDES, AND USES THEREOF

Document Type and Number:

WIPO Patent Application WO2000056866

Kind Code:

A9

Abstract:

The present invention relates to human Akt3 proteins and polypeptides. The invention also relates to isolated nucleic acids encoding human Akt3, to vectors containing them and to their therapeutic uses, in particular for gene therapy. Expression of Akt3 inhibits cell death associated with hypoxia, apoptosis or necrosis.

Inventors:

GUO KUN (US)
PAGNONI MARCO F (US)
CLARK KENNETH L (GB)
IVASHCHENKO YURI D (US)

Application Number:

PCT/US2000/006574

Publication Date:

August 29, 2002

Filing Date:

March 14, 2000

Export Citation:

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Assignee:

AVENTIS PHARM PROD INC (US)
GUO KUN (US)
PAGNONI MARCO F (US)
CLARK KENNETH L (GB)
IVASHCHENKO YURI D (US)

International Classes:

C12N15/113; A61K9/127; A61K35/76; A61K38/00; A61K39/395; A61K47/36; A61K47/42; A61K47/46; A61K48/00; A61P1/16; A61P9/10; A61P13/12; A61P37/06; A61P43/00; C07K16/40; C12N1/19; C12N1/21; C12N5/10; C12N7/00; C12N9/12; C12N15/09; C12Q1/48; G01N33/15; G01N33/50; G01N33/53; G01N33/566; C12R1/01; C12R1/645; C12R1/91; (IPC1-7): C12N9/12; C07K14/47; C12N15/63; C12N5/10; C12P21/00; C07K16/40; A61K38/45; A61P9/10; A61K48/00

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