Title:
AMINO ACID LINKED PEG-LIPID CONJUGATES
Document Type and Number:
WIPO Patent Application WO/2011/139343
Kind Code:
A3
Abstract:
New lipid-amino acid-polyethylene glycol (L-AA-PEG) conjugates are described. Amino acid are used as a backbone to conjugate lipids and PEG chains. L-AA-PEGs may be selected to optimize formulations of pharmaceuticals and cosmetics, among other uses.
Inventors:
WU NIAN (US)
KELLER BRIAN CHARLES (US)
KELLER BRIAN CHARLES (US)
Application Number:
PCT/US2011/000745
Publication Date:
April 05, 2012
Filing Date:
April 28, 2011
Export Citation:
Assignee:
WU NIAN (US)
KELLER BRIAN CHARLES (US)
KELLER BRIAN CHARLES (US)
International Classes:
C07C233/49; A61K8/45; A61K31/221; C07D207/416; C07J9/00
Domestic Patent References:
| WO2008027260A2 | 2008-03-06 |
Foreign References:
| US20100099738A1 | 2010-04-22 | |||
| US20100210518A1 | 2010-08-19 |
Other References:
VERONESE, FRANCESCO M.: "Peptide and protein PEGylation: a review of problems and solutions.", BIOMATERIALS., vol. 22, 2001, pages 405 - 417
HEYES, JAMES ET AL.: "Synthesis and characterization of novel poly(ethylene glycol)-lipid conjugates suitable for use in drug delivery.", JOURNAL OF CONTROLLED RELEASE., vol. 112, 2006, pages 280 - 290
HEYES, JAMES ET AL.: "Synthesis and characterization of novel poly(ethylene glycol)-lipid conjugates suitable for use in drug delivery.", JOURNAL OF CONTROLLED RELEASE., vol. 112, 2006, pages 280 - 290
Attorney, Agent or Firm:
PEDERSON, Lee (Sleepy Eye, MN, US)
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