Title:
ANALGESIC COMPOUNDS, THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Document Type and Number:
WIPO Patent Application WO2005035485
Kind Code:
A3
Abstract:
New analgesic compounds, which are prepared by the hydrolysis of N-acylated 4-hydroxyphenylamine derivatives, their synthesis and pharmaceutical compositions containing them are disclosed. These compounds surprisingly possess high analgesic activity with little hepatotoxic effect, making them more useful than conventional non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of chronic pain.
Inventors:
BAZAN NICOLAS G
VACCARINO ANTHONY
SUNKEL CARLOS
BUILLA JULIO ALVAREZ
VACCARINO ANTHONY
SUNKEL CARLOS
BUILLA JULIO ALVAREZ
Application Number:
PCT/US2004/033609
Publication Date:
June 09, 2005
Filing Date:
October 12, 2004
Export Citation:
Assignee:
FOUNDATION FOR THE LSU HEALTH (US)
International Classes:
C07C311/19; (IPC1-7): C07C311/19; A61K31/20; A61P29/02
Foreign References:
| US5554636A | 1996-09-10 | |||
| US5621110A | 1997-04-15 |
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