Title:
ANIMAL MODELS OF DUCHENNE MUSCULAR DYSTROPHY
Document Type and Number:
WIPO Patent Application WO/2014/117045
Kind Code:
A3
Abstract:
The present invention provides transgenic, large non-human animal models of Duchenne muscular dystrophy, Becker muscular dystrophy, and DMD-associated dilated cardiomyopathy, as well as methods of using such animal models in the identification and characterization of therapies for Duchenne muscular dystrophy, Becker muscular dystrophy, and DMD-associated dilated cardiomyopathy.
Inventors:
ROGERS CHRISTOPHER S (US)
SWART JOHN R (US)
SWART JOHN R (US)
Application Number:
PCT/US2014/013083
Publication Date:
October 09, 2014
Filing Date:
January 26, 2014
Export Citation:
Assignee:
EXEMPLAR GENETICS LLC (US)
International Classes:
A01K67/00; A01K67/027; C12N15/00
Foreign References:
| US20090235368A1 | 2009-09-17 | |||
| US20120220037A1 | 2012-08-30 |
Other References:
BURKHARDT.: "Generation of a tailored pig model of Duchenne muscular dystrophy.", PH.D. THESIS, 2012, pages 6 - 7, Retrieved from the Internet [retrieved on 20140408]
DATABASE GENBANK 25 July 2002 (2002-07-25), "Cloning vector pPGKneo-II, complete sequence.", accession no. F335420.3.
DATABASE GENBANK 16 August 2012 (2012-08-16), "Pig DNA sequence from clone CH 242-9G11 on chromosome X", accession no. U 582789.7
DATABASE GENBANK 25 July 2002 (2002-07-25), "Cloning vector pPGKneo-II, complete sequence.", accession no. F335420.3.
DATABASE GENBANK 16 August 2012 (2012-08-16), "Pig DNA sequence from clone CH 242-9G11 on chromosome X", accession no. U 582789.7
Attorney, Agent or Firm:
LOGUE, Holly (Los Angeles, CA, US)
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