ANTAGONISTS OF ALPHA-MELANOCYTE STIMULATING HORMONANTAGONISTS OF ALPHA-MELANOCYTE STIMULATING HORMONE AND METHODS BASED THEREON E AND METHODS BASED THEREON

Title:

ANTAGONISTS OF ALPHA-MELANOCYTE STIMULATING HORMONANTAGONISTS OF ALPHA-MELANOCYTE STIMULATING HORMONE AND METHODS BASED THEREON E AND METHODS BASED THEREON

Document Type and Number:

WIPO Patent Application WO1996022760

Kind Code:

A3

Abstract:

Peptide antagonists of alpha-melanocyte stimulating hormone are disclosed, together with methods of inhibiting the effects of alpha-melanocyte stimulating hormone on cells or tissues sensitive to that hormone. In particular, methods for lightening the pigmentation of skin and for treating malignant melanoma, as well as kits for practicing the invention are also disclosed.

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Inventors:

QUILLAN J MARK (US)
JAYAWICKREME CHANNA K (US)
LERNER MICHAEL R (US)

Application Number:

PCT/US1996/000404

Publication Date:

September 26, 1996

Filing Date:

January 16, 1996

Export Citation:

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Assignee:

QUILLAN J MARK (US)
JAYAWICKREME CHANNA K (US)
LERNER MICHAEL R (US)

International Classes:

A61K38/00; A61P5/00; A61P17/00; A61P35/00; C07K5/087; C07K5/097; C07K14/68; C07K14/685; (IPC1-7): A61K/

Other References:

JOURNAL OF BIOLOGICAL CHEMISTRY, 1994, Volume 269, JAYAWICKREME et al., "Discovery and Structure Function Analysis of Alpha-Melanocyte-Stimulating Hormone Antagonists", pages 29846-29854.
See also references of EP 0804217A4

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