ANTI-AGING AGENT OR LIFE-EXTENDING AGENT - UNIV TOKYO WOMENS MEDICAL

Title:

ANTI-AGING AGENT OR LIFE-EXTENDING AGENT

Document Type and Number:

WIPO Patent Application WO/2020/149218

Kind Code:

A1

Abstract:

The purpose of the present invention is to enable preventing aging or extending the life of a human or nonhuman organism with a method other than restricting calories or administering metformin.　It is possible to prevent aging or extend the life of a human or nonhuman organism by administering an agent that contains A) a xanthine oxidase/xanthine dehydrogenase inhibitor.　It is further possible to prevent aging or extend the life of a human or nonhuman organism by combining A) the xanthine oxidase/xanthine dehydrogenase inhibitor and B) hypoxanthine or a compound that can be converted to hypoxanthine in the body, and administering these simultaneously or administering these as a mixed agent or kit agents.

Inventors:

MITANI SHOHEI (JP)
MOIZUMI SAWAKO (JP)
IZUHARA LUNA (JP)
KAMATANI NAOYUKI (JP)

Application Number:

PCT/JP2020/000551

Publication Date:

July 23, 2020

Filing Date:

January 10, 2020

Export Citation:

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Assignee:

UNIV TOKYO WOMENS MEDICAL (JP)
STAGEN CO LTD (JP)

International Classes:

A61K31/403; A61K31/415; A61K31/426; A61K31/444; A61K31/519; A61K31/522; A61K31/7076; A61K31/708; A61K45/00; A61P43/00

Domestic Patent References:

WO2018092911A1

2018-05-24

Foreign References:

JP2018135278A

2018-08-30

Other References:

ALLISON, B.J. ET AL.: "Divergence of mechanistic pathways mediating cardiovascular aging and developmental programming of cardiovascular disease", THE FASEB JOURNAL, vol. 30, 2016, pages 1968 - 1975, XP055725903, ISSN: 0892-6638